Chemotaxis, viability, and labeling stability of leukocytes labeled with (99m)Tc-exametazime stabilized with methylene blue.

Stabilized with Methylene Blue

The in vitro viability, chemotaxis, and labeling stability of leukocytes labeled using 99mTc-exametazime stabilized with methylene blue were evaluated and compared with those obtained using nonstabilized 99mTc-exametazime. Methods: Two identical leukocyte populations, from 30 healthy donors, were labeled simultaneously using freshly prepared and 2-h-old stabilized 99mTc-exametazime. The followi...

Are leukocytes labeled with stabilized 99mTc-HMPAO becoming activated during labeling?

HMPAO Becoming Activated During Labeling?

TO THE EDITOR: We read with interest the recent article by Robins et al. (1) in which they reported biokinetic data of leukocytes labeled with stabilized 99mTc-HMPAO (exametazime) by a method that had earlier been described by their group in this journal (2) and elsewhere (3), with minor differences in methodology and results. Labeling white cells with technetium rather than indium has obvious ...

Comparison of Pretinning Methods to Label Leukocytes with Technetium-99m

Leukocytes labeled with technetium-99m using pretinning with stannous complexes of pyrophosphate, glucoheptonate, and gentisic acid were compared with respect to labeling efficiency, time required for labeling, in vitro cell viability, initial lung transit, and image quality following reinjection into normal volunteers. Gentisic acid pretinning was the best method, offering the shortest prepara...

Radiopharmacy Comparison of Pretinning Methods to Label Leukocytes with Technetium-99m

Leukocytes labeled with technetium-99m using pretinning with stannous complexes of pyrophosphate, glucoheptonate, and gentisic acid were compared with respect to labeling efficiency, time required for labeling, in vitro cell viability, initial lung transit, and image quality following reinjection into normal volunteers. Gentisic acid pretinning was the best method, offering the shortest prepara...